The meeting was held at the Presidential Palace in the presence of Second Vice President Mohammad Sarwar Danish and CEO Abdullah Abdullah.
Khalilzad said the US will continue its efforts with the Afghan peace process alongside the leadership of the Afghan government, the statement said.
Ghani thanked Khalilzad for his briefing and for his efforts and said that “we welcome any efforts to bring lasting peace in Afghanistan.”
However, the statement did not provide further details about the meeting.
On Friday, Khalilzad met with Qatar’s Deputy Prime Minister and Minister of Foreign Affairs, Sheikh Mohamed bin Abdulrahman Al Thani, while in Doha.
The two officials discussed ways of achieving peace and stability in Afghanistan and Qatar’s role in the peace process in the country, The Peninsula Qatar reported.
Khalilzad returned to Kabul on Saturday after his first visit last Sunday where he met with a wide range of stakeholders.
The US Embassy in Kabul said in a statement after his initial visit that Khalilzad met with President Ashraf Ghani and Chief Executive Abdullah Abdullah, as well as representatives of a variety of political groups, key civil society organizations including the High Peace Council, and Afghan media.
In his meetings, Khalilzad asked for cooperation from all sides to bring an end to the conflict and called on the parties to facilitate dialogue by forming inclusive negotiating teams.
Recalling the sacrifices of the Afghan people over many years of war, Khalilzad said: “We, in cooperation with the Afghan people and government, want to make a peaceful Afghanistan where all Afghans see themselves included.”
Khalilzad’s 11-day trip has included meetings with officials in Afghanistan, Pakistan, the United Arab Emirates (UAE), Qatar, and Saudi Arabia.